Sperm DNA fragmentation testing: when and why?

Sperm DNA fragmentation testing: when and why?

tau.amegroups.com © Translational Andrology and Urology. All rights reserved. Guideline is information intended to advise people on how something should be done or what something should be, according to Cambridge Dictionary (1). In a medical context, “guidelines are a series of suggestions, issued by official bodies or by independent experts, for the conduct of medical practice. They include ad...

Measure of sperm DNA fragmentation (SDF): how, why and when?

Sperm DNA fragmentation testing

The editors of this book, Drs. Ashok Agarwal, Ahmad Majzoub, Chak-Lam Cho and Sandro Esteves, are to be congratulated for bringing together an extensive tome on the evaluation and management of sperm DNA fragmentation. The perspectives from North America, South America, Europe, Asia and the rest of the world provide an interesting snapshot into management of the unique phenomenon of sperm DNA d...

Sperm DNA damage diagnostics: when and why

tau.amegroups.com © Translational Andrology and Urology. All rights reserved. Sperm DNA damage is the major cause of defective sperm function. DNA damage includes DNA denaturation and sperm DNA fragmentation (SDF) and maybe the common underlying aetiology of infertility, recurrent spontaneous abortion (RSA) preand post-implantation losses, accelerated aging, and childhood cancer (1). Oxidative ...

Clinical usefulness of sperm DNA fragmentation testing

tau.amegroups.com © Translational Andrology and Urology. All rights reserved. The search for the best biomarker for the diagnosis of male infertility is more evident in recent years as conventional semen analysis is not always an optimal predictor of male fertility. Since the advent of the intra-cytoplasmic sperm injection (ICSI) for male factor infertility, the pace of research related to sper...